TRERF1

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Database of Genomic Structural Variation (dbVar)

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transcriptional regulating factor 1

RAPA; BCAR2; TREP132; TReP-132; HSA277276; dJ139D8.5

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Go to complete Gene record for TRERF1

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This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Chromosome: 6; NC_000006.12 (42224933..42452216, complement)

NC_000006 Chromosome 6 Reference GRCh38.p7 Primary Assembly (location A)

NC_000006 Chromosome 6 Reference GRCh37.p13 Primary Assembly (location B)

NC_018917 Chromosome 6 Alternate CHM1_1.1

See 1000 Genomes Browser (GRCh37.p13)

publications in PubMed explicitly cited by the gene record in OMIM.

publications in PubMed limited specific clinical research.

sorted by relevance are shown below.Click to see all (22) citations.

TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone.

Gizard F, Robillard R, Gross B, Barbier O, Rvillion F, Peyrat JP, Torpier G, Hum DW, Staels BGizard F,

. Mol Cell Biol, 2006 Oct. PMID 17015480

TReP-132 controls cell proliferation by regulating the expression of the cyclin-dependent kinase inhibitors p21WAF1/Cip1 and p27Kip1.

Gizard F, Robillard R, Barbier O, Quatannens B, Faucompr A, Rvillion F, Peyrat JP, Staels B, Hum DWGizard F,

. Mol Cell Biol, 2005 Jun. PMID 15899840

Identification of a novel breast-cancer-anti-estrogen-resistance (BCAR2) locus by cell-fusion-mediated gene transfer in human breast-cancer cells.

Dorssers LC, Veldscholte JDorssers LC,

. Int J Cancer, 1997 Aug 7. PMID 9259413

The transcriptional regulating protein of 132 kDa (TReP-132) differentially influences steroidogenic pathways in human adrenal NCI-H295 cells.

Gizard F, Teissier E, Dufort I, Luc G, Luu-The V, Staels B, Hum DWGizard F,

. J Mol Endocrinol, 2004 Apr. PMID 15072559

Function of the transcriptional regulating protein of 132 kDa (TReP-132) on human P450scc gene expression.

Gizard F, El-Alfy M, Duguay Y, Lavalle B, DeWitte F, Staels B, Beatty BG, Hum DWGizard F,

. Endocr Res, 2002 Nov. PMID 12530663

Gene links to PubMed derived from omim_pubmed_cited links

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